Article
N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination.
BMC molecular biology - 11 Oct 2006
Urakov Valery N, Valouev Igor A, Kochneva-Pervukhova Natalia V, Packeiser Anna N, Vishnevsky Alexander Yu, Glebov Oleg O, Smirnov Vladimir N, Ter-Avanesyan Michael D
Abstract excerpt
BACKGROUND: Termination of translation in eukaryotes requires two release factors, eRF1, which recognizes all three nonsense codons and facilitates release of the nascent polypeptide chain, and eRF3 stimulating translation termination in a GTP-depended manner. eRF3 from different organisms possess a highly conservative C region (eRF3C), which is responsible for the function in translation termination, and almost...
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