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Article

Mutations in the exons and exon-intron junction regions of human cytochrome P-4502E1 gene and alcoholism.

Alcoholism, clinical and experimental research - 1 Apr 1999

Itoga S, Nomura F, Harada S, Tsutsumi M, Takase S, Nakai T

Abstract excerpt

Cytochrome P-4502E1 (CYP2E1) is a major component of the microsomal ethanol-oxidizing system (MEOS) and is also involved in the metabolism of a variety of foreign compounds, including carcinogens. It has been shown that there are interindividual variations in the expression of human CYP2E1. Gene-environmental interactions have been suggested to account for the difference. In this study, we screened nine exons and...

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Identifiers

PMID: 10235271
DOI: 10.1111/j.1530-0277.1999.tb04526.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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