Article
[Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions].
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence - 1 Feb 1998
Itoga S, Harada S, Nomura F, Nakai T
Abstract excerpt
Cytochrome P450-2E1 (CYP2E1) is a major component of the microsomal ethanol-oxidizing system (MEOS) and is also involved in the metabolism of a variety of foreign compounds including carcinogens. It has been shown that there is an interindividual variation in the expression of human hepatic CYP2E1. Gene-environmental interactions have been suggested to account for the difference. In this study, we screened nine...
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