Article
Cytochrome P450 2E1 variable number tandem repeat polymorphisms and health risks: a genotype-phenotype study in cancers associated with drinking and/or smoking.
Molecular medicine reports - 1 Aug 2012
Catanzaro Irene, Naselli Flores, Saverini Marghereth, Giacalone Antonio, Montalto Giuseppe, Caradonna Fabio
Abstract excerpt
Cytochrome P450 2E1 (CYP2E1) is one of the main enzymes involved in the oxidation of ethanol and in the transformation of a number of potentially dangerous compounds. It has various polymorphic sites, one of which is a variable number tandem repeat (VNTR) polymorphism previously described in the 5'-flanking region. The aim of this study was to investigate the genotype-phenotype association between CYP2E1 VNTR...
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