Article
Genetic polymorphism of alcohol-metabolizing enzyme and alcohol dependence in Polish men.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Mar 2010
Cichoz-Lach H, Celiński K, Wojcierowski J, Słomka M, Lis E
Abstract excerpt
Alcohol dependence poses a serious medical and sociological problem. It is influenced by multiple environmental and genetic factors, which may determine differences in alcohol metabolism. Genetic polymorphism of the enzymes involved in alcohol metabolism is highly ethnically and race dependent. The purpose of this study was to investigate the differences, if present, in the allele and genotype frequency of...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Alcohol Dehydrogenase
- Alcoholism
- Case-Control Studies
- Cytochrome P-450 CYP2E1
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Poland
- Polymorphism, Genetic
- Young Adult