Article
906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.
Journal of human genetics - 1 Jan 2002
Saito Susumu, Iida Aritoshi, Sekine Akihiro, Ogawa Chie, Kawauchi Saori, Higuchi Shoko, Ohno Machi, Nakamura Yusuke
Abstract excerpt
We screened DNAs from 48 Japanese individuals for single-nucleotide polymorphisms (SNPs) in genes encoding 13 cytochrome P450 (CYP) enzymes and 14 aldehyde dehydrogenases (ALDHs) by directly sequencing their entire genomic regions except for repetitive elements. This approach identified 810 SNPs and 96 insertion/deletion polymorphisms among the 27 genes. Of the 810 SNPs, 229 were identified among the CYP genes...
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