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Article

Inactivation gating of Kv4 potassium channels: molecular interactions involving the inner vestibule of the pore.

The Journal of general physiology - 1 May 1999

Jerng H H, Shahidullah M, Covarrubias M

Abstract excerpt

Kv4 channels represent the main class of brain A-type K+ channels that operate in the subthreshold range of membrane potentials (Serodio, P., E. Vega-Saenz de Miera, and B. Rudy. 1996. J. Neurophysiol. 75:2174- 2179), and their function depends critically on inactivation gating. A previous study suggested that the cytoplasmic NH2- and COOH-terminal domains of Kv4.1 channels act in concert to determine the fast...

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Identifiers

PMID: 10228180
DOI: 10.1085/jgp.113.5.641
PMCID: PMC2222907

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Source receipt: pubmed, retrieved 7 Sept 2026.

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