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Article

Slow inactivation in voltage-gated sodium channels: molecular substrates and contributions to channelopathies.

Cell biochemistry and biophysics - 1 Jan 2001

Vilin Y Y, Ruben P C

Abstract excerpt

Slow inactivation in voltage-gated sodium channels is a biophysical process that governs the availability of sodium channels over extended periods of time. Slow inactivation, therefore, plays an important role in controlling membrane excitability, firing properties, and spike frequency adaptation. Defective slow inactivation is associated with several diseases of cell excitability, such as hyperkalemic periodic...

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Identifiers

PMID: 11892790
DOI: 10.1385/CBB:35:2:171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Slow inactivation in voltage-gated sodium channels: molecular substrates and contributions to channelopathies.PMID 11892790Read ↗

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