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Article

Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region.

Genesis (New York, N.Y. : 2000) - 1 Mar 2005

Lin Wei, Jing Naihe, Basson M Albert, Dierich Andrée, Licht Jonathan, Ang Siew-Lan

Abstract excerpt

Sef and Sprouty proteins function as feedback antagonists of fibroblast growth factor (Fgf) signaling in zebrafish embryos. To study the role of Sef in mice, we generated Sef homozygous mutant animals. These animals are viable and show normal expression of mid-hindbrain genes at embryonic days 8.5 and 9.5. To investigate the possibility of functional synergism between Sef and Sprouty proteins, we electroporated...

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Identifiers

PMID: 15729686
DOI: 10.1002/gene.20103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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