Article
Coordinated activity of Spry1 and Spry2 is required for normal development of the external genitalia.
Developmental biology - 1 Feb 2014
Ching Saunders T, Cunha Gerald R, Baskin Laurence S, Basson M Albert, Klein Ophir D
Abstract excerpt
Development of the mammalian external genitalia is controlled by a network of signaling molecules and transcription factors. Because FGF signaling plays a central role in this complicated morphogenetic process, we investigated the role of Sprouty genes, which are important intracellular modulators of FGF signaling, during embryonic development of the external genitalia in mice. We found that Sprouty genes are...
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