Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell-type specific utilization of multiple negative feedback loops generates developmental constancy.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jul 2005

Iwanami Masaki, Hiromi Yasushi, Okabe Masataka

Abstract excerpt

Signaling pathways generally contain multiple negative regulators that are induced by the signal they repress, constructing negative feedback loops. Although such negative regulators are often expressed in a tissue- or cell-type specific manner during development, little is known about the significance of their differential expression patterns and possible interactions. We show the role and interplay of two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epidermal Growth Factor
Share to Eye
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Feedback, Physiological

Share to Genes, ras

Share to Mitogen-Activated Protein Kinases

Share to Photoreceptor Cells, Invertebrate

Share to Receptors, Steroid

Source

Identifiers

PMID: 15966904
DOI: 10.1111/j.1365-2443.2005.00871.x

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell-type specific utilization of multiple negative feedback loops generates developmental constancy.PMID 15966904Read ↗

Sprouty gain of function disrupts lens cellular processes and growth by restricting RTK signaling.Semantic proximity Read ↗

An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg.Semantic proximity Read ↗

Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila.Semantic proximity Read ↗

Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network.Semantic proximity Read ↗

Yan regulates Lozenge during Drosophila eye development.Semantic proximity Read ↗

Reciprocal regulatory interactions between the Notch and Ras signaling pathways in the Drosophila embryonic mesoderm.Semantic proximity Read ↗

The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination.Semantic proximity Read ↗

SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development.Semantic proximity Read ↗

Antagonism of LIN-17/Frizzled and LIN-18/Ryk in nematode vulva induction reveals evolutionary alterations in core developmental pathways.Semantic proximity Read ↗

The feedback regulator Nord controls Dpp/BMP signaling via extracellular interaction with Dally in the <i>Drosophila</i> wingSemantic proximity Read ↗

Mutations modulating the Argos-regulated signaling pathway in Drosophila eye development.Semantic proximity Read ↗

Spry1 and Spry2 are necessary for eyelid closure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.