Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two loci, Tmevp2 and Tmevp3, located on the telomeric region of chromosome 10, control the persistence of Theiler's virus in the central nervous system of mice.

Genetics - 1 May 1999

Bihl F, Brahic M, Bureau J F

Abstract excerpt

Theiler's virus persistently infects the white matter of the spinal cord in susceptible strains of mice. This infection is associated with inflammation and primary demyelination and is studied as a model of multiple sclerosis. The H-2D gene is the major gene controlling viral persistence. However, the SJL/J strain is more susceptible than predicted by its H-2(s) haplotype. An (SJL/J x B10. S)F1 x B10.S backcross...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Microsatellite Repeats

Share to RNA, Viral

Share to Sex Factors

Share to Spinal Cord

Share to Telomere

Share to Theilovirus

Source

Open in PubMed Open full text

Identifiers

PMID: 10224268
DOI: 10.1093/genetics/152.1.385
PMCID: PMC1460584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two loci, Tmevp2 and Tmevp3, located on the telomeric region of chromosome 10, control the persistence of Theiler's virus in the central nervous system of mice.PMID 10224268Read ↗

Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system.Semantic proximity Read ↗

The genetics of the persistent infection and demyelinating disease caused by Theiler's virus.Semantic proximity Read ↗

Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases.Semantic proximity Read ↗

Tmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon.Semantic proximity Read ↗

Viral load and a locus on chromosome 11 affect the late clinical disease caused by Theiler's virus.Semantic proximity Read ↗

The interaction of two groups of murine genes determines the persistence of Theiler's virus in the central nervous system.Semantic proximity Read ↗

The infection of mouse by Theiler's virus: from genetics to immunology.Semantic proximity Read ↗

The shiverer mutation affects the persistence of Theiler's virus in the central nervous system.Semantic proximity Read ↗

CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology.Semantic proximity Read ↗

CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis.Semantic proximity Read ↗

Genetics of susceptibility to Theiler's virus infection.Semantic proximity Read ↗

Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreadingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.