Article
The infection of mouse by Theiler's virus: from genetics to immunology.
Immunological reviews - 1 Oct 1997
Monteyne P, Bureau J F, Brahic M
Abstract excerpt
Theiler's virus is a picornavirus of mouse which causes an acute encephalomyelitis followed by a persistent infection of the white matter of the spinal cord with chronic inflammation and demyelination. This late disease is studied as a model for multiple sclerosis. Inbred strains of mice differ i...
Topics
- Animals
- Genetic Predisposition to Disease
- H-2 Antigens
- Histocompatibility Antigen H-2D
- Interferon-gamma
- Mice
- Poliomyelitis
- Theilovirus
- Virus Latency