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Article

The infection of mouse by Theiler's virus: from genetics to immunology.

Immunological reviews - 1 Oct 1997

Monteyne P, Bureau J F, Brahic M

Abstract excerpt

Theiler's virus is a picornavirus of mouse which causes an acute encephalomyelitis followed by a persistent infection of the white matter of the spinal cord with chronic inflammation and demyelination. This late disease is studied as a model for multiple sclerosis. Inbred strains of mice differ in their susceptibility to persistent infection and demyelination. Resistant strains clear the infection after the acute...

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Source

Identifiers

PMID: 9416510
DOI: 10.1111/j.1600-065x.1997.tb01014.x

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The infection of mouse by Theiler's virus: from genetics to immunology.PMID 9416510Read ↗

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CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology.Semantic proximity Read ↗

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Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreadingSemantic proximity Read ↗

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