Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system.

doi:10.1038/ng0993-87

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Article

Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system.

Nature genetics - 1 Sept 1993

Bureau J F, Montagutelli X, Bihl F, Lefebvre S, Guénet J L, Brahic M

Abstract excerpt

Inbred strains of mice differ greatly in their susceptibility to the demyelinating disease caused by Theiler's Murine Encephalomyelitis Virus. In this murine disease, which is an animal model for the study of multiple sclerosis, demyelination depends on the persistent infection of the central ner...

Topics

Animals
Base Sequence
Brain
Chromosome Mapping
Crosses, Genetic
Female
Genetic Markers
Genetic Predisposition to Disease
H-2 Antigens
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Molecular Sequence Data
Poliomyelitis
Theilovirus
Virus Latency

Source

Open in PubMed

Identifiers

PMID: 8220433
DOI: 10.1038/ng0993-87

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8220433-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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