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Chinese hamster ovary cell mutants defective in glycosaminoglycan assembly and glucuronosyltransferase I.

The Journal of biological chemistry - 7 May 1999

Bai X, Wei G, Sinha A, Esko J D

Abstract excerpt

The proteoglycans of animal cells typically contain one or more heparan sulfate or chondroitin sulfate chains. These glycosaminoglycans assemble on a tetrasaccharide primer, -GlcAbeta1, 3Galbeta1,3Galbeta1,4Xylbeta-O-, attached to specific serine residues in the core protein. Studies of Chinese hamster ovary cell mutants defective in the first or second enzymes of the pathway (xylosyltransferase and...

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Identifiers

PMID: 10224052
DOI: 10.1074/jbc.274.19.13017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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