Article
Estradiol beta-D-xyloside, an efficient primer for heparan sulfate biosynthesis.
The Journal of biological chemistry - 15 Apr 1991
Lugemwa F N, Esko J D
Abstract excerpt
Animal cells utilize beta-D-xylosides as primers for glycosaminoglycan synthesis. However, most xylosides preferentially stimulate chondroitin sulfate synthesis and only weakly prime heparan sulfate synthesis. To test if the structure of the aglycone determines the type of glycosaminoglycan made, the priming activity of methyl, n-octyl, p-nitrophenyl, 4-methylumbelliferyl, trans,trans-farnesyl, cholesteryl, and...
Topics
- Animals
- Cell Division
- Cell Line
- Chromatography, Gel
- Cycloheximide
- Estradiol
- Glycosaminoglycans
- Glycosides
- Heparitin Sulfate
- Kinetics
- Mutation
- Proteoglycans
