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Article

Two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate.

The Journal of biological chemistry - 18 Nov 1994

Fritz T A, Gabb M M, Wei G, Esko J D

Abstract excerpt

We report that two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate in Chinese hamster ovary cells. The first enzyme initiates heparan sulfate biosynthesis and can be measured by the transfer of GlcNAc from UDP-GlcNAc to GlcUA beta 1-3Gal beta 1-O-naphthalenemethanol....

Topics

Animals
CHO Cells
Carbohydrate Sequence
Catalysis
Cricetinae
Heparitin Sulfate
Kinetics
Molecular Sequence Data
Mutation
N-Acetylglucosaminyltransferases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7961837

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7961837-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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