Article
Two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate.
The Journal of biological chemistry - 18 Nov 1994
Fritz T A, Gabb M M, Wei G, Esko J D
Abstract excerpt
We report that two N-acetylglucosaminyltransferases catalyze the biosynthesis of heparan sulfate in Chinese hamster ovary cells. The first enzyme initiates heparan sulfate biosynthesis and can be measured by the transfer of GlcNAc from UDP-GlcNAc to GlcUA beta 1-3Gal beta 1-O-naphthalenemethanol. The second enzyme catalyzes the polymerization of heparan sulfate and can be measured by the transfer of GlcNAc from...
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