Article
Decorin core protein secretion is regulated by N-linked oligosaccharide and glycosaminoglycan additions.
The Journal of biological chemistry - 30 Dec 2005
Seo Neung-Seon, Hocking Anne M, Höök Magnus, McQuillan David J
Abstract excerpt
Expression of decorin using the vaccinia virus/T7 expression system resulted in secretion of two distinct glycoforms: a proteoglycan substituted with a single chondroitin sulfate chain and N-linked oligosaccharides and a core protein glycoform substituted with N-linked glycans but without a glycosaminoglycan chain. In this report, we have addressed two distinct questions. What is the rate-limiting step in...
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