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Article

Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma.

Cancer letters - 8 Feb 1999

Oon C J, Chen W N, Zhao Y, Teng S W, Leong A L

Abstract excerpt

Vaccine escape hepatitis B virus surface antigen (HBsAg) mutants are capable of independent replication and have been implicated in acute hepatitis. We now report the detection of these mutants with changes at various positions of the antigenic 'a' determinant in human hepatocellular carcinoma (HCC). Southern blot analysis indicated that the HBsAg mutant with the Glycine to Arginine change at position 145 was...

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Identifiers

PMID: 10211946
DOI: 10.1016/s0304-3835(98)00314-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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