Article
Vaccine- and hepatitis B immune globulin-induced escape mutations of hepatitis B virus surface antigen.
Journal of biomedical science - 1 Jan 2000
Cooreman M P, Leroux-Roels G, Paulij W P
Abstract excerpt
Hepatitis B virus surface antigen (HBsAg) vaccination has been shown to be effective in preventing hepatitis B virus (HBV) infection. The protection is based on the induction of anti-HBs antibodies against a major cluster of antigenic epitopes of HBsAg, defined as the 'a' determinant region of small HBsAg. Prophylaxis of recurrent HBV infection in patients who have undergone liver transplantation for hepatitis...
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