Article
Detection of the GSTM1*0 allele by long polymerase chain reaction.
Pharmacogenetics - 1 Feb 1999
Kerb R, Brockmöller J, Sachse C, Roots I
Abstract excerpt
Approximately 50% of individuals in most human populations completely lack activity of the detoxifying enzyme glutathione S-transferase M1. The medical consequences of this deficiency have been extensively investigated in molecular epidemiological studies, but possible differences of the highly active homozygous genotype versus the moderately active heterozygous genotype could not be considered because many...
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