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Article

Characterization of a human glutathione S-transferase mu cluster containing a duplicated GSTM1 gene that causes ultrarapid enzyme activity.

Molecular pharmacology - 1 Dec 1997

McLellan R A, Oscarson M, Alexandrie A K, Seidegård J, Evans D A, Rannug A, Ingelman-Sundberg M

Abstract excerpt

The mu class glutathione S-transferase gene GSTM1 is polymorphic in humans, with approximately half of the Caucasian population being homozygous deleted for this gene. GSTM1 enzyme deficiency has been suggested to predispose people to lung and bladder cancer. Some people in a Saudi Arabian population, however, have been described previously with ultrarapid GSTM1 enzyme activity. Here we have evaluated the...

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Identifiers

PMID: 9415705
DOI: 10.1124/mol.52.6.958

Genes

GSTM1
GSTM2
GSTM5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of a human glutathione S-transferase mu cluster containing a duplicated GSTM1 gene that causes ultrarapid enzyme activity.PMID 9415705Read ↗

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Identification of the GST-T1 and GST-M1 null genotypes using high resolution melting analysis.Semantic proximity Read ↗

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