Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: application to glutathione transferase mu.

doi:10.1289/ehp.9298113

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Article

Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: application to glutathione transferase mu.

Environmental health perspectives - 1 Nov 1992

Bell D A, Thompson C L, Taylor J, Miller C R, Perera F, Hsieh L L, Lucier G W

Abstract excerpt

Several genes involved in the metabolism of carcinogens have been found to be polymorphic in human populations and are associated with increased risk of cancer at some sites. This study focuses on the polymorphic enzyme glutathione transferase mu (GT mu). Smokers with low lymphocyte GT mu activit...

Topics

Gene Deletion
Genotype
Glutathione Transferase
Humans
Lymphocytes
Polymerase Chain Reaction
Polymorphism, Genetic

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