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Article

Identification of the GST-T1 and GST-M1 null genotypes using high resolution melting analysis.

Chemical research in toxicology - 13 Jan 2012

Drobná Zuzana, Del Razo Luz Maria, Garcia-Vargas Gonzalo, Sánchez-Ramírez Blanca, González-Horta Carmen, Ballinas-Casarrubias Lourdes, Loomis Dana, Stýblo Miroslav

Abstract excerpt

Glutathione S-transferases, including GST-T1 and GST-M1, are known to be involved in the phase II detoxification pathways for xenobiotics as well as in the metabolism of endogenous compounds. Polymorphisms in these genes have been linked to an increased susceptibility to carcinogenesis and associated with risk factors that predispose to certain inflammatory diseases. In addition, GST-T1 and GST-M1 null genotypes...

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PMID: 22136492
DOI: 10.1021/tx200457u
PMCID: PMC3262591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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