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Article

Dystrophin and utrophin do not play crucial roles in nonmuscle tissues in mice.

Muscle & nerve - 1 Apr 1999

Rafael J A, Trickett J I, Potter A C, Davies K E

Abstract excerpt

The loss of full-length dystrophin from skeletal muscle leads to the clinical features of Duchenne muscular dystrophy. Both Dp71, a C-terminal dystrophin isoform, and the dystrophin-related protein, utrophin, are present at high levels in many nonmuscle tissues. To investigate the roles of these proteins in nonmuscle tissues, mice were generated null for utrophin, and deficient in all dystrophin isoforms. These...

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Source

Identifiers

PMID: 10204788
DOI: 10.1002/(sici)1097-4598(199904)22:4<517::aid-mus14>3.0.co;2-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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