Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synergetic effect between interleukin-1 receptor antagonist allele (IL1RN*2) and MHC class II (DR17,DQ2) in determining susceptibility to systemic lupus erythematosus.

Lupus - 1 Jan 1999

Tjernström F, Hellmer G, Nived O, Truedsson L, Sturfelt G

Abstract excerpt

We investigated whether IL1RN alleles separately or in combination with MHC class II variants, contribute to susceptibility to SLE and to analysed if IL1RN alleles are markers of disease severity. We investigated 81 patients from a defined area in southern Sweden diagnosed between 1981-1992 and 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Susceptibility
Share to DNA, Satellite
Share to Histocompatibility Antigens Class II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DQ Antigens

Share to HLA-DR Antigens

Share to Interleukin 1 Receptor Antagonist Protein

Share to Lupus Erythematosus, Systemic

Share to Sialoglycoproteins

Source

Identifiers

PMID: 10192503
DOI: 10.1191/096120399678847560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10192503-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synergetic effect between interleukin-1 receptor antagonist allele (IL1RN*2) and MHC class II (DR17,DQ2) in determining susceptibility to systemic lupus erythematosus.PMID 10192503Read ↗

Interleukin–1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosusSemantic proximity Read ↗

IL1RN*2 allele of IL-1receptor antagonist VNTR polymorphism is associated with susceptibility to ankylosing [corrected] spondylitis in Indian patients.Semantic proximity Read ↗

Interleukin-1 receptor antagonist gene polymorphism and rheumatoid arthritis.Semantic proximity Read ↗

Polymorphism of the interleukin-1 receptor antagonist gene: a factor in susceptibility to rheumatoid arthritis in a Spanish population.Semantic proximity Read ↗

Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis.Semantic proximity Read ↗

Interleukin-1 receptor antagonist gene polymorphism in chinese patients with systemic lupus erythematosus.Semantic proximity Read ↗

Relationship Between Polymorphisms of Interleukin-1 Receptor Antagonist (IL-1Ra) Genes and Susceptibility to Systemic Lupus Erythematosus in Iranian Population.Semantic proximity Read ↗

Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.Semantic proximity Read ↗

Interleukin-1 receptor antagonist allele (IL1RN*2) associated with nephropathy in diabetes mellitus.Semantic proximity Read ↗

Potential influence of interleukin-1 receptor antagonist gene polymorphism on knee osteoarthritis risk.Semantic proximity Read ↗

Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro.Semantic proximity Read ↗

Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.