Article
IL1RN*2 allele of IL-1receptor antagonist VNTR polymorphism is associated with susceptibility to ankylosing [corrected] spondylitis in Indian patients.
Clinical rheumatology - 1 May 2008
Agrawal Sumeet, Srivastava Rajni, Sharma Banwari, Pandya Sapan, Misra Ramnath, Aggarwal Amita
Abstract excerpt
Despite strong linkage of ankylosing spondylitis (AS) with human leukocyte antigen (HLA) B27, its contribution to disease susceptibility is only 15%, and additional genetic factors are likely to be involved in AS. Interleukin (IL)-1 locus has been linked to AS in European population. Thus, we studied IL-1 receptor antagonist polymorphism in Indian patients with AS. One hundred and sixty-two patients with AS and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
