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Article

Interleukin–1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus

1 Aug 1994

Abstract excerpt

OBJECTIVE: We have previously described associations between an allele of the interleukin-1 receptor antagonist gene (IL1RN) and several inflammatory diseases. In this study we tested the IL1RN gene as a possible marker in patients with systemic lupus erythematosus (SLE). METHODS: Eighty-one SLE patients and 261 ethnically matched control subjects were genotyped by polymerase chain reaction. RESULTS: We found an...

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PMID: 7945503
DOI: 10.1002/art.1780370917

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