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Article

Potential influence of interleukin-1 receptor antagonist gene polymorphism on knee osteoarthritis risk.

Disease markers - 1 Jan 2010

Swellam Menha, Mahmoud Magda Sayed, Samy Nervana, Gamal Ali Ahmed

Abstract excerpt

OBJECTIVES: Genes encoding for cytokines have been associated with susceptibility for joint osteoarthritis (OA) and interleukin (IL)-1 gene is supposed to be involved in the cartilage destruction process. In this regard, interleukin-1 receptor antagonist (IL-1RA) competing with IL-1 for binding to its receptor may act as an inhibitor of cartilage breakdown. We assessed the association of primary knee OA with...

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Identifiers

PMID: 20592454
DOI: 10.3233/DMA-2010-0708
PMCID: PMC3833698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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