Article
Interleukin-1 receptor antagonist allele (IL1RN*2) associated with nephropathy in diabetes mellitus.
Human genetics - 1 Mar 1996
Blakemore A I, Cox A, Gonzalez A M, Maskil J K, Hughes M E, Wilson R M, Ward J D, Duff G W
Abstract excerpt
We have previously found association between an allele of the interleukin-1 (IL-1) receptor antagonist gene (IL1RN) and several inflammatory diseases, where IL-1 has been implicated in the inflammatory mechanism. We have now, therefore, tested the association of this specific allele (IL1RN*2) with complications of diabetes which have an inflammatory tissue component. We have tested the allele frequency of IL1RN*2...
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