Article
Relationship Between Polymorphisms of Interleukin-1 Receptor Antagonist (IL-1Ra) Genes and Susceptibility to Systemic Lupus Erythematosus in Iranian Population.
Current rheumatology reviews - 1 Jan 2020
Ganjali Rashin, Afshari Jalil T, Rezaieyazdi Zahra, Khodashahi Mandana, Brook Azam, Mazhani Maryam, Hatef Mohamad R, Abbasi Mahnaz
Abstract excerpt
OBJECTIVES: Interleukin (IL)-1 has a major role in cell destruction and inflammation. IL-1 receptor antagonist (IL-1RN or IL-1Ra) is a natural anti-inflammatory molecule that blocks IL-1. We intended to determine whether IL-1RN or IL-1Ra variable number tandem repeat (VNTR) polymorphism is associated with susceptibility to systemic lupus erythematosus (SLE) in a series of patients in the Northeastern part of...
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