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Article

The Pharmacology of ATP-Sensitive K+ Channels (KATP).

Handbook of experimental pharmacology - 1 Jan 2021

Li Yiwen, Aziz Qadeer, Tinker Andrew

Abstract excerpt

ATP-sensitive K+ channels (KATP) are inwardly-rectifying potassium channels, broadly expressed throughout the body. KATP is regulated by adenine nucleotides, characteristically being activated by falling ATP and rising ADP levels thus playing an important physiological role by coupling cellular metabolism with membrane excitability. The hetero-octameric channel complex is formed of 4 pore-forming inward rectifier...

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PMID: 34247283
DOI: 10.1007/164_2021_466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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