Article
Muscle KATP channels: recent insights to energy sensing and myoprotection.
Physiological reviews - 1 Jul 2010
Flagg Thomas P, Enkvetchakul Decha, Koster Joseph C, Nichols Colin G
Abstract excerpt
ATP-sensitive potassium (K(ATP)) channels are present in the surface and internal membranes of cardiac, skeletal, and smooth muscle cells and provide a unique feedback between muscle cell metabolism and electrical activity. In so doing, they can play an important role in the control of contractility, particularly when cellular energetics are compromised, protecting the tissue against calcium overload and fiber...
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