Article
Behavioral responses to stress are intact in CRF-deficient mice.
Brain research - 16 Oct 1999
Dunn A J, Swiergiel A H
Abstract excerpt
Corticotropin-releasing factor (CRF) has been implicated in endocrine and behavioral responses associated with stress. We have now studied the behavior of mice lacking the CRF gene (CRFko), comparing them to wild-type (WT) mice. Behaviors were observed in untreated mice, as well as following restraint or intraperitoneal administration of mouse interleukin-1beta (mIL-1beta). In the multicompartment chamber (MCC),...
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