Article
Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice.
Neuroscience - 1 Jan 2003
Schmidt M V, Schmidt M, Oitzl M S, Müller M B, Ohl F, Wurst W, Holsboer F, Levine S, De Kloet E R
Abstract excerpt
During postnatal development, mice undergo a so-called stress hyporesponsive period, which is characterized by low basal corticosterone levels and the inability of mild stressors to induce a corticosterone response. The stress hyporesponsiveness is in part regulated by maternal factors. Twenty-four hours of deprivation results in an activation of basal and stress-induced corticosterone and a down-regulation of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.