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Article

A note on power approximations for the transmission/disequilibrium test.

American journal of human genetics - 1 Apr 1999

Knapp M

Abstract excerpt

The transmission/disequilibrium test (TDT) is a popular method for detection of the genetic basis of a disease. Investigators planning such studies require computation of sample size and power, allowing for a general genetic model. Here, a rigorous method is presented for obtaining the power approximations of the TDT for samples consisting of families with either a single affected child or affected sib pairs....

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Identifiers

PMID: 10090903
DOI: 10.1086/302334
PMCID: PMC1377842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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