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Article

General equations for Pt, Ps, and the power of the TDT and the affected-sib-pair test.

American journal of human genetics - 1 Nov 2000

McGinnis R

Abstract excerpt

Several equations are highlighted here, whose algebraic symmetries and generality make them very useful for understanding and comparing the properties of the transmission disequilibrium test (TDT) and affected sib-pair test. Methods using the equations are also presented that yield precise estimates of sample sizes needed for genome scans or for testing a single candidate gene, and these power methods are shown...

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Identifiers

PMID: 11013135
DOI: 10.1016/S0002-9297(07)62965-6
PMCID: PMC1288577

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