Article
The apolipoprotein E epsilon 4 allele is not associated with psychiatric symptoms or extrapyramidal signs in probable Alzheimer's disease.
Neurology - 1 Sept 1997
Lopez O L, Kamboh M I, Becker J T, Kaufer D I, DeKosky S T
Abstract excerpt
The objective of our study was to examine the relationship between the presence of the apolipoprotein E (apo E) epsilon 4 allele, psychiatric symptoms, and extrapyramidal signs (EPS) in probable Alzheimer's disease (AD). The apo E epsilon 4 allele modifies the risk and age at onset of AD. However, it still needs to be determined whether it is a marker for specific clinical subgroups. The frequency of clinical...
Topics
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Basal Ganglia Diseases
- Female
- Humans
- Male
- Mental Disorders
- Neurologic Examination