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Article

Susceptibility to spina bifida; an association study of five candidate genes.

Annals of human genetics - 1 Sept 1998

Morrison K, Papapetrou C, Hol F A, Mariman E C, Lynch S A, Burn J, Edwards Y H

Abstract excerpt

Clues regarding candidate genes which influence susceptibility to spina bifida and anencephaly come from the identification of folate-associated risk factors and from studies of mouse mutants showing neural tube anomalies. On this basis we selected five candidate genes; CBS, MS, MTHFR, T (Brachyury) and BRCA1 for genetic analysis in 31 Dutch and 48 British NTD families. Ten polymorphisms, two for each gene, were...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
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Source

Identifiers

PMID: 10088035
DOI: 10.1046/j.1469-1809.1998.6250379.x

Genes

MTHFR
CBS
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Susceptibility to spina bifida; an association study of five candidate genes.PMID 10088035Read ↗

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