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Article

Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population.

American journal of medical genetics. Part A - 1 Jan 2011

Carter Tonia C, Pangilinan Faith, Troendle James F, Molloy Anne M, VanderMeer Julia, Mitchell Adam, Kirke Peadar N, Conley Mary R, Shane Barry, Scott John M, Brody Lawrence C, Mills James L

Abstract excerpt

Individual studies of the genetics of neural tube defects (NTDs) contain results on a small number of genes in each report. To identify genetic risk factors for NTDs, we evaluated potentially functional single nucleotide polymorphisms (SNPs) that are biologically plausible risk factors for NTDs but that have never been investigated for an association with NTDs, examined SNPs that previously showed no association...

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Source

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Identifiers

PMID: 21204206
DOI: 10.1002/ajmg.a.33755
PMCID: PMC3503244

Genes

LEPR
COMT
MTHFR
PDGFRA

Variants

rs3127334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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