Article
Genetic mapping of the human homologue (T) of mouse T(Brachyury) and a search for allele association between human T and spina bifida.
Human molecular genetics - 1 May 1996
Morrison K, Papapetrou C, Attwood J, Hol F, Lynch S A, Sampath A, Hamel B, Burn J, Sowden J, Stott D, Mariman E, Edwards Y H
Abstract excerpt
We describe a genetic analysis of the human homologue (T) of the mouse T (Brachyury) gene; human T was recently cloned in our laboratory. The protein product of the T gene is a transcription factor crucial in vertebrates for the formation of normal mesoderm. T mutant Brachyury mice die in midgest...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
