Article
Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutants.
Proceedings of the National Academy of Sciences of the United States of America - 16 Mar 1999
Flores C, Engels W
Abstract excerpt
We have cloned a mutS homolog from Drosophila melanogaster called spellchecker1 (spel1) and have constructed spel1 mutant flies. MutS proteins promote the correction of DNA mismatches and serve important roles in DNA replication, recombination, and repair. The spel1 gene belongs to a subfamily of mutS first characterized by the MSH2 gene of yeast and which also includes hMSH2, one of the two major hereditary...
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