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Article

Visualization of receptor-mediated endocytosis in yeast.

Molecular biology of the cell - 1 Mar 1999

Mulholland J, Konopka J, Singer-Kruger B, Zerial M, Botstein D

Abstract excerpt

We studied the ligand-induced endocytosis of the yeast alpha-factor receptor Ste2p by immuno-electron microscopy. We observed and quantitated time-dependent loss of Ste2p from the plasma membrane of cells exposed to alpha-factor. This ligand-induced internalization of Ste2p was blocked in the well-characterized endocytosis-deficient mutant sac6Delta. We provide evidence that implicates furrow-like invaginations...

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Identifiers

PMID: 10069819
DOI: 10.1091/mbc.10.3.799
PMCID: PMC25203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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