Article
Characterization of Vta1p, a class E Vps protein in Saccharomyces cerevisiae.
The Journal of biological chemistry - 19 Mar 2004
Shiflett Shelly L, Ward Diane McVey, Huynh Dinh, Vaughn Michael B, Simmons Jennifer C, Kaplan Jerry
Abstract excerpt
We identified VTA1 in a screen for mutations that result in altered vacuole morphology. Deletion of VTA1 resulted in delayed trafficking of the lipophilic dye FM4-64 to the vacuole and altered vacuolar morphology when cells were exposed to the dye 5-(and 6)-carboxy-2',7'-dichlorofluorescein diacetate (CDCFDA). Deletion of class E vacuolar protein sorting (VPS) genes, which encode proteins that affect...
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