Article
Yeast exocytic v-SNAREs confer endocytosis.
Molecular biology of the cell - 1 Oct 2000
Gurunathan S, Chapman-Shimshoni D, Trajkovic S, Gerst J E
Abstract excerpt
In yeast, homologues of the synaptobrevin/VAMP family of v-SNAREs (Snc1 and Snc2) confer the docking and fusion of secretory vesicles at the cell surface. As no v-SNARE has been shown to confer endocytosis, we examined whether yeast lacking the SNC genes, or possessing a temperature-sensitive allele of SNC1 (SNC1(ala43)), are deficient in the endocytic uptake of components from the cell surface. We found that...
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