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Article

Actin and fimbrin are required for the internalization step of endocytosis in yeast.

The EMBO journal - 1 Jul 1993

Kübler E, Riezman H

Abstract excerpt

In Saccharomyces cerevisiae, alpha-factor is internalized by receptor-mediated endocytosis and transported via vesicular intermediates to the vacuole where the pheromone is degraded. Using beta-tubulin and actin mutant strains, we showed that actin plays a direct role in receptor-mediated internalization of alpha-factor, but is not necessary for transport from the endocytic intermediates to the vacuole....

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Identifiers

PMID: 8335001
DOI: 10.1002/j.1460-2075.1993.tb05947.x
PMCID: PMC413538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Actin and fimbrin are required for the internalization step of endocytosis in yeast.PMID 8335001Read ↗

Direct evidence for ligand-induced internalization of the yeast alpha-factor pheromone receptor.Semantic proximity Read ↗

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Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway.Semantic proximity Read ↗

Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeast.Semantic proximity Read ↗

Differential requirements for actin during yeast and mammalian endocytosis.Semantic proximity Read ↗

S. cerevisiae alpha pheromone receptors activate a novel signal transduction pathway for mating partner discrimination.Semantic proximity Read ↗

Coupling actin dynamics to the endocytic process in Saccharomyces cerevisiae.Semantic proximity Read ↗

Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis.Semantic proximity Read ↗

Visualization of receptor-mediated endocytosis in yeast.Semantic proximity Read ↗

Role of type I myosins in receptor-mediated endocytosis in yeast.Semantic proximity Read ↗

The ankyrin repeat-containing protein Akr1p is required for the endocytosis of yeast pheromone receptors.Semantic proximity Read ↗

The conserved Pkh-Ypk kinase cascade is required for endocytosis in yeast.Semantic proximity Read ↗

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