Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein carbonyl accumulation in aging dauer formation-defective (daf) mutants of Caenorhabditis elegans.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 1999

Yasuda K, Adachi H, Fujiwara Y, Ishii N

Abstract excerpt

It is known that a dauer-constitutive gene, daf-2, controls both larval development and adult life span in Caenorhabditis elegans. The increased life span caused by the daf-2 mutation can be enhanced by a daf-12 mutation and suppressed by a daf-16 mutation. In order to determine the correlation between longevity and oxidative stress in these mutants, protein carbonyl (a good indicator of oxidative damage during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Forkhead Transcription Factors
Share to Free Radicals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helminth Proteins

Share to Indicators and Reagents

Share to Life Cycle Stages

Share to Longevity

Share to Receptor, Insulin

Share to Spectrophotometry, Ultraviolet

Source

Identifiers

PMID: 10051850
DOI: 10.1093/gerona/54.2.b47

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein carbonyl accumulation in aging dauer formation-defective (daf) mutants of Caenorhabditis elegans.PMID 10051850Read ↗

Testing the rate-of-living/oxidative damage theory of aging in the nematode model Caenorhabditis elegans.Semantic proximity Read ↗

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans.Semantic proximity Read ↗

A C. elegans mutant that lives twice as long as wild type.Semantic proximity Read ↗

Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2.Semantic proximity Read ↗

Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span.Semantic proximity Read ↗

Genes that regulate both development and longevity in Caenorhabditis elegans.Semantic proximity Read ↗

Methyl 3,4-Dihydroxybenzoate Enhances Resistance to Oxidative Stressors and Lifespan in C. elegans Partially via daf-2/daf-16.Semantic proximity Read ↗

A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans.Semantic proximity Read ↗

Oxidative stress and aging in Caenorhabditis elegans.Semantic proximity Read ↗

Hormesis in Caenorhabditis elegans dauer-defective mutants.Semantic proximity Read ↗

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans.Semantic proximity Read ↗

Genes that may modulate longevity in C. elegans in both dauer larvae and long-lived daf-2 adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.