A C. elegans mutant that lives twice as long as wild type.

doi:10.1038/366461a0

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Article

A C. elegans mutant that lives twice as long as wild type.

Nature - 2 Dec 1993

Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R

Abstract excerpt

We have found that mutations in the gene daf-2 can cause fertile, active, adult Caenorhabditis elegans hermaphrodites to live more than twice as long as wild type. This lifespan extension, the largest yet reported in any organism, requires the activity of a second gene, daf-16. Both genes also re...

Topics

Animals
Caenorhabditis elegans
Disorders of Sex Development
Genes, Helminth
Larva
Longevity
Mutation
Reproduction
Temperature

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