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Article

Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span.

Mechanisms of ageing and development - 1 Nov 2002

Yanase Sumino, Yasuda Kayo, Ishii Naoaki

Abstract excerpt

Oxidative damage shortens the life span of the nematode Caenorhabditis elegans (C. elegans), even in an age-1 mutant that is characterized by a long life and oxygen resistance. We found that daily short-term exposure (3 h) to hyperoxia further extended the life span of age-1, a phenomenon known as an adaptive response. age-1 also showed resistance to paraquat and heat. Acute hyperoxic treatment did not extend the...

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PMID: 12470895
DOI: 10.1016/s0047-6374(02)00093-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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