Article
Integrative genomic analysis of blood pressure and related phenotypes in rats.
Disease models & mechanisms - 1 May 2021
Takeuchi Fumihiko, Liang Yi-Qiang, Isono Masato, Tajima Michiko, Cui Zong Hu, Iizuka Yoko, Gotoda Takanari, Nabika Toru, Kato Norihiro
Abstract excerpt
Despite remarkable progress made in human genome-wide association studies, there remains a substantial gap between statistical evidence for genetic associations and functional comprehension of the underlying mechanisms governing these associations. As a means of bridging this gap, we performed genomic analysis of blood pressure (BP) and related phenotypes in spontaneously hypertensive rats (SHR) and their...
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